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Preclinical experiments with testosterone implants induced cervical-uterine tumors in mice which metastasized in some instances. Some reviews indicate that administration of testosterone cypionate in females can augment the susceptibility to hepatoma as well as raise the number of tumors. Clinical experiments have described cases of hepatocellular carcinoma in extended-expression superior-dose therapy.six
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Its benefit compared to other testosterone derivatives may be the sluggish level of launch immediately after injection and lengthier 50 percent-existence. It was developed by the organization Pharmacia and Upjohn and FDA approved on July twenty five, 1979.
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